AB1368 ULTRASONOGRAPHIC EVALUATION OF THE KNEE AND MUSCLE ARCHITECTURE IN OSTEOARTHRITIS AND RHEUMATOID ARTHRITIS

نویسندگان

چکیده

Background Involvement of lower extremity joints in both rheumatoid arthritis (RA) and osteoarthritis (OA) is an important cause declined functional status. Deterioration skeletal muscle performance further contributes to disability. Quadriceps plays role most daily activities. Measuring thickness pennation angle quadriceps compartments can provide knowledge regarding condition. Objectives Aim investigate structural inflammatory changes knee joint architecture RA, OA patients a group healthy subjects. Methods Twenty RA 20 with radiographic disease meeting Kellgren-Lawrence grade 2 above were consecutively recruited, absence exclusion criteria. volunteers similar demographics recruited as control group. Knee symptoms disability evaluated by Lequesne Index (LKI). Disease activity was DAS28-CRP patients. ultrasonographic measurements thickness, subcutaneous fat tissue vastus muscles. Suprapatellar, lateral medial examined for effusion, synovial hypertrophy, power Doppler (PD) degenerative changes. Results Demographics clinical features subjects results evaluation are presented Table 1. LKI scores significantly higher when compared (p=0.004). Rate increased groups comparison controls (p=0.013). None the had PD activity. No differences observed rectus femoris, muscles between groups. Vastus medialis intermedius angles reduced controls, but reached statistical significance only (3.56 ± 6.37 vs 4.89 7.14 7.29 4.93, p=0.038). Demographics, findings (n=20 ) Control p Age, years ¶ 58.44 6.68 54.67 7.15 55.11 5.89 0.178 Gender, female µ 17 (85) 15 (75) 16 (80) 0.732 BMI 30.05 3.88 28.29 4.78 28.27 3.34 0.343 Duration diagnosis, months 11.95 17.15 14.80 8.50 0.023 9.37 2.65 6.95 3.38 0.004 2.59 1.10 Presence effusion 9 (45) 4 (20) 0.166 SH 11 (55) 8 (40) 0.626 degeneration 13 (65) 7 (35) 0.013 Muscle mm VM 14.09 4.17 15.38 5.15 14.57 3.41 0.243 VL 17.17 3.53 16.96 4.98 16.66 3.18 0.985 VI 10.54 10.49 3.32 10.67 1.83 0.926 RF 13.01 3.92 13.74 3.78 13.63 3.49 0.879 SFT 12.59 5.79 13.81 7.10 12.53 5.20 0.969 Pennation angle, degree 5.50 7.01 6.94 8.29 9.05 5.10 0.244 13.61 13.44 3.40 13.29 3.25 0.703 3.56 4.93 0.038 : mean SD, µ: number (%),LKI: Index, KL: Kellgren – Lawrence grade, SH: VM: medialis, VL: lateralis, VI: intermedius, RF: SFT: Conclusion In our study ultrasound patients.VM These may indicate impairment due involvement. References [1]Hsieh LF, et al. Isokinetic isometric testing musculature mild Arch Phys Med Rehabil. 1987;68:294-7. [2]Ruhdorfer A, Association pain reduction thigh strength - cross-sectional analysis including 4553 initiative participants. Osteoarthritis Cartilage. 2017;25:658-666. Acknowledgements I have no acknowledgements declare. Disclosure Interests declared

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ژورنال

عنوان ژورنال: Annals of the Rheumatic Diseases

سال: 2022

ISSN: ['1468-2060', '0003-4967']

DOI: https://doi.org/10.1136/annrheumdis-2022-eular.4112